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Important Patient Information
PODOFILOX - TOPICAL SOLUTION (poh-DOFF-ih-lox) COMMON BRAND NAME(S): CondyloxIMPORTANT NOTE: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your health care professional. Always seek the advice of your health care professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your health care professional. This information does not contain any assurances that this product is safe, effective, or appropriate for you.
USES: Podofilox solution is used to treat warts on the outside of the genitals. Podofilox belongs to a group of drugs called antimitotics. It causes the wart to die and eventually peel off.
HOW TO USE: First read the manufacturers patient information leaflet provided by your pharmacist before you start using podofilox and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Use this medication every 12 hours for 3 days, followed by no treatment for the next 4 days. This 7-day treatment cycle can be repeated for 4 weeks in a row until there is no visible wart. Follow your doctor's directions exactly. Apply as directed by your doctor in the morning and just before going to bed. Leave the solution on between applications, or use as directed. In the morning, wash the treated area with soap and water to remove the solution, then apply the morning dose. Do not leave podofilox on longer than prescribed by your doctor. Before applying the medication, wash the area to be treated with soap and water, and dry thoroughly. Apply this medication to the affected area with the supplied application device. For warts within skin folds, pull the skin fold open and apply the medication. Allow the medication to dry before allowing skin folds around any warts to return to their normal positions. Apply only enough of this medication to cover the warts your doctor has directed you to treat. Avoid applying this medication to the surrounding skin. Wash your hands with soap and water after each application. Do not cover the treated area with bandages or other waterproof dressings. Covering the area with cotton gauze or cotton underwear for the genital area is permitted. Use this medication regularly in order to get the most benefit from it. To help you remember, use a calendar to mark the days you will be applying the medication each week. This medication is for application to skin only. Do not use in the eyes, inside the rectum, or inside the vagina, and do not take by mouth. If you get any of this medication in your eyes, flush with a steady stream of tap water for 15 minutes. Contact your doctor if you have any vision change, eye swelling, or persistent eye pain. Tell your doctor if your condition persists or worsens after 4 weeks of treatment or if new growths appear during treatment.
SIDE EFFECTS: Redness, swelling, itching, burning, pain/tenderness, mild bleeding, or stinging may occur in the treated areas. Less common side effects may include peeling/flaking/scabbing/crusting, dryness, tingling, stinging, skin color change, or headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If the skin reaction is severe (formation of sores/ulcers, severe bleeding), tell your doctor immediately. Podofilox treatment may need to be temporarily stopped so that the skin can heal. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of infection at the site of treatment (e.g., spreading area of skin redness, milky discharge). A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: See also Side Effects section. Before using podofilox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent/unhealed surgery on the skin area to be treated. Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system problems, HIV infection (human immunodeficiency virus). This medication is not a cure for genital warts. These warts are caused by a virus called human papillomavirus (HPV). Since podofilox does not destroy the virus but only helps to remove the wart, new warts may form, even while you are being treated. You may also be able to infect any sexual partner who comes into contact with the areas of skin infected with HPV. To reduce the risk of spreading HPV to others, always use effective barrier protections (e.g., latex or polyurethane condoms, dental dams) during all sexual activity. Consult your doctor or pharmacist for more details. During treatment of genital warts, avoid all sexual contact while the solution is on the skin. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.
OVERDOSE: This product may be harmful if swallowed. If overdose or swallowing is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature at 59-86 degrees F (15-30 degrees C). Avoid freezing this medication or exposing it to high heat. Discard any medication that has been frozen. Keep all medicines away from children and pets. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
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